Please read following example to understand the phenomena: let's assume we want to measure EPHA3. The problem is that the genes symbols are not unambiguous and the HUGO database we use for the selection of the probe sets also includes overlapping gene symbols. I have selected gene XXX but the results are for gene YYY - why is this?! As the different names can overlap, we recommend to cross-check the identity of the selected gene. KM-plot recognizes 70,632 gene symbols (including HUGO Gene Nomenclature Committee approved official gene symbols, previous symbols and aliases - all these are listed in the results page). Databases and clinical data are supervised and extended regularly. The two patient cohorts are compared by a Kaplan-Meier survival plot, and the hazard ratio with 95% confidence intervals and logrank P value are calculated. To analyze the prognostic value of a particular gene, the patient samples are split into two groups according to various quantile expressions of the proposed biomarker. The database is handled by a PostgreSQL server, which integrates gene expression and clinical data simultaneously.
Survival information are downloaded from GEO, EGA and TCGA.
Peter plotter drawing 1965 programming free#
Gene expression data and relapse free and overall The background database is manually curated. For a general citation of the KM-plotter, please use: Lanczky A, Gyorffy B: Web-Based Survival Analysis Tool Tailored for Medical Research (KMplot): Development and Implementation, J Med Internet Res, 2021 Jul 26 23(7):e27633.